Phytochemical Screening, Antioxidative, Antiobesity, Antidiabetic and Antimicrobial Investigations of Artemisia scoparia Grown in Palestine

Validating ethnobotanical data from underexplored traditional plant remedies provides an infinite source of new pharmaceutical chemicals. The purpose this study was to determine the phytochemical composition and several biological activities (antioxidant, anti-lipase, anti-?-amylase, anti-?-glucosidase, antimicrobial) aqueous, ethanol, hexane, acetone Artemisia scoparia leaf extracts. An exhaustive technique employed extract A. four At same time, standard analytical biochemical assays were utilized preliminary screening, anti-DPPH, anti-?-amylase activities. Furthermore, antimicrobial effects against seven microbial strains evaluated using a broth micro-dilution assay. Acetone exhibited highest DPPH scavenging anti-?-glucosidase (IC50 = 21.87 ± 0.71, 149.75 1.33 µg/mL, respectively), as well ethanol extract, activity 251 1.34 µg/mL) while aqueous had best anti-lipase 102 0.27 among other Moreover, hexane has more powerful Methicillin-Resistant Staphylococcus aureus (MRSA), aureus, Proteus vulgaris, Pseudomonas aeruginosa than Ciprofloxacin Ampicillin antibiotics with MICs 0.78 0.01, 0.39 1.56 0.22 respectively. In addition, extracts have antifungal power Fluconazole (1.56 µg/mL). outcomes current indicated that acetone, promising antioxidant, effects, interesting potential. potentially bioactive compounds can be selected for further isolation purification. clinical investigations in vivo approaches should implemented confirm benefits these diabetes, obesity, oxidative stress, infections.